Translational control and autism-like behaviors
نویسندگان
چکیده
منابع مشابه
Translational control and autism-like behaviors
AUTISM SPECTRUM DISORDERS (ASD) CONSIST OF A SPECTRUM OF NEURODEVELOPMENTAL DISEASES WITH THREE SALIENT FEATURES: reduced social interactions, impaired communication and repetitive/stereotyped behaviors. In a recent study we found that increased eIF4E (eukaryotic initiation factor 4E)-dependent protein synthesis as a result of genetic deletion of Eif4ebp2 (eIF4E-binding protein 2) in mice, stim...
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Abnormal immune responses have been reported to be associated with autism. A number of studies showed that cytokines were increased in the blood, brain, and cerebrospinal fluid of autistic subjects. Elevated IL-6 in autistic brain has been a consistent finding. However, the mechanisms by which IL-6 may be involved in the pathogenesis of autism are not well understood. Here we show that mice wit...
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ژورنال
عنوان ژورنال: Cellular Logistics
سال: 2013
ISSN: 2159-2799
DOI: 10.4161/cl.24551